Let's Not Be Hasty


Dr Robert Malone is in the news a lot lately, much amplified by the Covid/vaccine fringe. As the purported 'inventor of mRNA vaccines', his words carry enormous weight with people who think science is done by naming people and listing their credentials. He insists that vaccine development - using that technology he claims to have invented - has been rushed.

Now, Malone has his name on in the region of 100 papers. I was poking through them, and came upon this which, in light of the views expressed above, is quite extraordinary. The proposal is for 'FastVax' vaccine development using nucleic acid technologies as a rapid response to a novel threat. Does this ring any bells re: present circumstances?


Isn't that amazing? This is Dr "Vaccines-rushed" we're talking about here. He may not have written it, but with his name on it, we can assume that he endorsed the content, back in 2013. Reading through 2022 eyes, it anticipates nicely what happened with SARS-CoV-2. Because we were already in the state of readiness called for in the article - several platforms tested and ready to go - we were able to get a genome sequence, email it around the world and design epitope sequences in hours. And, because of the sense of urgency, telescope the approvals process massively, and have a large number of public-spirited volunteers to take the risk on behalf of the rest of us (many of whom still insist "I ain't taking no experimental gene therapy vaccine!"). End points in trials were reached much more quickly because the disease was common.

Admittedly, the skin-patch delivery method wasn't used; other than that, it is uncannily prescient. As a Proof of Concept, they were able to design a vaccine for H7N9 in 20 hours. They then go on to discuss how the bureaucratic and perhaps overcautious FDA approval process can be streamlined into this proposal, complete with Emergency Use Authorisation. And this is, one must assume, 'vaccination in a pandemic'.

There's more. 

Recall that Malone regularly complains that mRNA vaccine-generated SARS-CoV-2 'spike' protein is inherently cytotoxic (which debatable claim scoots past the fact that the sole evidence for that comes from spikes attached to viruses!). 

"two distinct T cell responses are generated: (1) a CD8+ cytotoxic T lymphocyte immune response that is critical for pathogen clearance, and (2) a CD4+ T helper immune response that is essential for robust and sustained antibody and cytotoxic T lymphocyte responses. After initial exposure to pathogen, memory T cells are established that respond more rapidly and efficiently upon subsequent exposure.

Because epitopes provide the essential information needed to trigger a protective immune response, epitope-based vaccines can be developed to recreate this response." (my bold).

The cytotoxicity here is not the same as that I mentioned above, which relates to interaction of spike with surface proteins (when attached to a virus!). Nor is it even a property of spike per se, but a consequence of the immune response; the very thing that we wish to invoke in 'safe' mimicry of infection, part of which is the destruction of cells deemed to have gone 'off-message'. This triggers downstream immune pathways and is a normal, and vital, part of the immune response.

Malone knows this.


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